Generic
Fexofenadine Hydrochloride
Indications
Axodin is suitable for alleviating symptoms related to seasonal allergic rhinitis in adults and children. It is also suitable for the treatment of simple skin manifestations of chronic idiopathic urticaria.
Pharmacology
Fexofenadine hydrochloride is an antihistamine with selective peripheral H1 receptor antagonist activity. is rapidly absorbed after oral administration, reaching maximum blood concentration in 23 hours. Does not appear to cross the blood-brain barrier
Dosage & Administration
Seasonal allergic rhinitis
adults and children under 12 years old:
Tablets: 60 mg twice a day or 120 mg once a day or 180 mg once a day
In case of renal failure: 60 mg
a day Children 6 to 11 years old :
Tablets: 30 mg twice a day or 60 mg once a day
In case of renal failure: 30 mg once a day
Children aged 2 to 11 years
Suspension: 30 mg twice a day or 5 ml
In In case of renal failure: 30 mg or 5 ml once a day
Chronic idiopathic urticaria
adults and children 12 years and older:
Tablets: 60 mg twice a day or 120 mg once a day or 180 mg once a day
Renal failure:
60 mg per day Children 6 to 11 years old:
Tablets: 30 mg twice a day or 60 mg once a day
In case of renal failure: 30 mg once a day
Children from 6 months to under 2 years:
Suspension: 15 mg or 2.5 ml (1/ 2 teaspoons) twice a day
In case of renal failure: 15 mg or 2.5 ml (1/2 teaspoon) once a day
Children 2 to 11 years old:
Suspension: 30 mg or 5 ml (1 teaspoon) twice a day a day
If kidney failure: 30 mg or 5 ml (1 teaspoon) once a day
Interaction
When combined with erythromycin or ketoconazole, the plasma concentration of fexofenadine hydrochloride increases. Antacids containing aluminum hydroxide and magnesium hydroxide can reduce the absorption of Axodin.
Contraindications
Patients known to be allergic to fexofenadine hydrochloride or any of its components are contraindicated.
Side Effects
Common side effects are headache, fatigue, drowsiness, nausea, dry mouth and gastrointestinal disorders.
Pregnancy & Lactation
The US FDA classifies fexofenadine hydrochloride pregnancy as C. Therefore, fexofenadine hydrochloride should be avoided during pregnancy and breastfeeding, unless the potential benefit to the other party outweighs the possible risk to the fetus.
Precautions & Warnings
Elderly patients and patients with impaired renal function should be used with caution.
Therapeutic Class
Non-sedating antihistamines
Storage Conditions
Store in a dry place away from light and heat. Keep out of reach of children