Pasthil is a line of herbal lozenges (pastilles) produced by Leda Pharma (Leda İlaç), a pharmaceutical company based in Turkey. These products are primarily used to soothe throat irritation, relieve coughs, and support the immune system. They are generally classified as food supplements rather than prescription medications. Here are the key details about Pasthil products: 1. Common Ingredients Depending on the specific variety, Pasthil lozenges typically contain a combination of: Propolis: Known for its natural antibacterial and antiviral properties. Ginger & Turmeric: Used for their anti-inflammatory effects. Vitamin C: To support the immune system. Menthol/Peppermint: To provide a cooling sensation and open the airways. Honey & Lemon: To coat and soothe a dry or scratchy throat. 2. Popular Variants Leda Pharma usually offers several "flavors" or formulations, such as: Pasthil Ginger & Lemon: Focuses on refreshing the throat and reducing nausea or irritation. Pasthil Propolis: Aimed at stronger immune support and treating more painful throat conditions. Pasthil Orange: Often packed with extra Vitamin C. 3. What is it used for? Sore Throat: Relieving pain and scratchiness. Hoarseness: Helping to clear the voice. Cough Relief: Suppressing the urge to cough by keeping the throat moist. Mouth Hygiene: Refreshing the breath and providing mild antiseptic benefits. 4. How to Use Dosage: Usually, it is recommended to dissolve one lozenge slowly in the mouth every 2–3 hours. Caution: Because they often contain sugar or sweeteners, people with diabetes should check the specific packaging. They are generally not recommended for very young children due to the risk of choking.
Generic
Fenofibrate
Indications
Fenofibrate is used to treat hyperlipidemias of type lla, llb, III, IV, and V in people who haven't responded well to diet and other treatments.
Pharmacology
Fibric acid derivative fenofibrate. After oral ingestion, fenofibrate is rapidly hydrolyzed to its pharmacologically active form, fenofibric acid. Total cholesterol, LDL cholesterol, Apo-lipoprotein B, total triglycerides, and VLDL cholesterol are all reduced by fenofibric acid. Furthermore, Fenofibrate treatment causes an increase in HDL and apo-proteins apoAI apoAII. Fenofibrate.
Dosage & Administration
The initial dose of Fenofibrate for adult patients with hypercholesterolemia or mixed hyperlipidemia is 200 mg per day.
The initial dose for adult patients with hypertriglyceridemia is 67 to 200 mg per day.
Individualize the dose based on the patient's response. Fenofibrate should be taken with a meal to maximize the medication's bioavailability.
Interaction
Warfarin's anticoagulant effects have been reported to be potentiated by fenofibrate. It may improve glucose tolerance and have an additive effect when combined with an anti-diabetic drug. Cyclosporine nephrotoxicity may be increased by fenofibrate.
Contraindications
Hypersensitivity to Fenofibrate, severe renal or hepatic impairment, existing gall bladder disease, breast-feeding mothers, and photosensitivity to ketoprofen are all contraindications to taking Fenofibrate.
Side Effects
Myotoxicity (nausea, anorexia, gastric pain), pruritus, urticaria, impotence, as well as headache, dizziness, vertigo, fatigue, and hair loss.
Pregnancy & Lactation
Pregnant women should avoid taking fenofibrate.
Precautions & Warnings
Patients with renal disease should be given extra attention because progressive increases in serum creatinine concentration or failure to follow dosage guidelines can lead to myotoxicity; discontinue if myotoxicity is suspected or if creatinine kinase concentration rises significantly. For the first year, liver function tests are recommended every three months.
Therapeutic Class
Fibrates
Storage Conditions
Keep the temperature below 30°C and away from light and moisture. Keep out of children's reach.