New Product
Pasthil.
Pasthil is a line of herbal lozenges (pastilles) produced by Leda Pharma (Leda İlaç), a pharmaceutical company based in Turkey. These products are primarily used to soothe throat irritation, relieve coughs, and support the immune system. They are generally classified as food supplements rather than prescription medications. Here are the key details about Pasthil products: 1. Common Ingredients Depending on the specific variety, Pasthil lozenges typically contain a combination of: Propolis: Known for its natural antibacterial and antiviral properties. Ginger & Turmeric: Used for their anti-inflammatory effects. Vitamin C: To support the immune system. Menthol/Peppermint: To provide a cooling sensation and open the airways. Honey & Lemon: To coat and soothe a dry or scratchy throat. 2. Popular Variants Leda Pharma usually offers several "flavors" or formulations, such as: Pasthil Ginger & Lemon: Focuses on refreshing the throat and reducing nausea or irritation. Pasthil Propolis: Aimed at stronger immune support and treating more painful throat conditions. Pasthil Orange: Often packed with extra Vitamin C. 3. What is it used for? Sore Throat: Relieving pain and scratchiness. Hoarseness: Helping to clear the voice. Cough Relief: Suppressing the urge to cough by keeping the throat moist. Mouth Hygiene: Refreshing the breath and providing mild antiseptic benefits. 4. How to Use Dosage: Usually, it is recommended to dissolve one lozenge slowly in the mouth every 2–3 hours. Caution: Because they often contain sugar or sweeteners, people with diabetes should check the specific packaging. They are generally not recommended for very young children due to the risk of choking.
Candoral® (Miconazole 2% w/w) 20mg Oral Gel (15 g)
Generic
Miconazole Nitrate
Indications
Miconazole Nitrate oral gel is indicated-
For the treatment of oral and gastrointestinal candidiasis.
For eradication of fungal colonization in the mouth and gastrointestinal tract.
For the treatment of super infections due to gram-positive bacteria.
Pharmacology
Miconazole has a low oral bioavailability (25-30%) due to intestinal absorption. Miconazole is absorbed systemically after being given as an oral gel. Miconazole is bound to plasma proteins (88.2%), primarily serum albumin and red blood cells, after absorption (10.6 percent ). Miconazole oral gel is mostly metabolized after it is absorbed.
Administration & Dosage
Oropharyngeal candidosis-
Infants 4-24 months: 1.25 ml (1⁄4 measuring spoon) of gel, applied 4 times day after meals.
Adult and children 2 years of age and older: 2.5 ml (1⁄2 measuring spoon) of gel, applied 4 times a day after meals.
Gastrointestinal tract candidosis-
Infants (4 months of age or above): Children and adults who have difficulty swallowing tablets: 20 mg per kg body weight per day, in four divided doses. The daily dose should not exceed 250 mg (10 ml gel) four times daily.
Missed Dose: Apply the missed dose as soon as you remember. In case of next dosing time, omit the missed
dose and continue your usual course.
Interaction
Concurrent treatment with Terfenadine, Astemizole, and Cisapride should be avoided because Miconazole may inhibit their metabolism, causing these products to precipitate, according to in vitro studies.
Miconazole may cause a delay in the metabolism of phenytoin and cyclosporine, which could lead to phenytoin and cyclosporine toxicity, respectively.
Contraindications
Miconazole should not be used in patients who have a history of hypersensitivity to the active ingredient.
Side Effect
Long-term use may cause nausea and vomiting, as well as diarrhea and allergic reactions.
Pregnancy & Lactation
There is no information about Miconazole oral gel's safety during pregnancy. Miconazole oral gel should be avoided during pregnancy if at all possible, or the risks should be weighed against the benefits. Miconazole should be administered with caution to a nursing woman because many drugs are excreted in human milk.
Precautions & Warnings
On the off chance that the concomitant utilize of Miconazole and anticoagulant is considered, the anti-coagulant impact ought to be observed and titrated. Miconazole and phenytoin plasma level ought to too be checked when utilized concomitantly. In newborn children and youthful children, caution must be taken to guarantee that the gel does not deter the throat.
Therapeutic Class
Aural Anti-fungal arrangements
Storage Conditions
Protect from light and moisture by storing below 30°C. Keep the medicine out of children's reach.