Pasthil is a line of herbal lozenges (pastilles) produced by Leda Pharma (Leda İlaç), a pharmaceutical company based in Turkey. These products are primarily used to soothe throat irritation, relieve coughs, and support the immune system. They are generally classified as food supplements rather than prescription medications. Here are the key details about Pasthil products: 1. Common Ingredients Depending on the specific variety, Pasthil lozenges typically contain a combination of: Propolis: Known for its natural antibacterial and antiviral properties. Ginger & Turmeric: Used for their anti-inflammatory effects. Vitamin C: To support the immune system. Menthol/Peppermint: To provide a cooling sensation and open the airways. Honey & Lemon: To coat and soothe a dry or scratchy throat. 2. Popular Variants Leda Pharma usually offers several "flavors" or formulations, such as: Pasthil Ginger & Lemon: Focuses on refreshing the throat and reducing nausea or irritation. Pasthil Propolis: Aimed at stronger immune support and treating more painful throat conditions. Pasthil Orange: Often packed with extra Vitamin C. 3. What is it used for? Sore Throat: Relieving pain and scratchiness. Hoarseness: Helping to clear the voice. Cough Relief: Suppressing the urge to cough by keeping the throat moist. Mouth Hygiene: Refreshing the breath and providing mild antiseptic benefits. 4. How to Use Dosage: Usually, it is recommended to dissolve one lozenge slowly in the mouth every 2–3 hours. Caution: Because they often contain sugar or sweeteners, people with diabetes should check the specific packaging. They are generally not recommended for very young children due to the risk of choking.
Indications of Betapro 2.5 Tablet
Bisoprolol is suitable for -
Hypertension, Angina pectoris , Moderate to severe heart failure
Pharmacology of Betapro 2.5 Tablet
Bisoprolol hemifumarate is the most selective ß1 blocker. Compared to any other beta-blocker available to date, it has the highest affinity for ß1 receptors. It selectively blocks β1 adrenergic receptors in the heart and vascular smooth muscle, reduces heart rate and cardiac output, resulting in a reduction in arterial hypertension .In patients using non-selective β1 blockers, β blockers may have an adverse effect on lipid metabolism, but bisoprolol will not cause any change in cholesterol during long-term treatment, including cardioprotective HDL cholesterol.
Dosage & Administration of Betapro 2.5 Tablet
Hypertension: The dosage of bisoprolol should be individualized according to the needs of the patient. The usual starting dose is 5 mg once a day. In some patients, 2.5 mg may be a suitable starting dose. If the hypotensive effect of 5 mg is insufficient, the dose can be increased to 10 mg and then, if necessary, to , to 20 mg once daily.
Angina: generally 10 mg per day (5 mg may be sufficient for some patients), up to 20 mg per day.
Heart failure: initially 1.25 mg once daily (morning) for 1 week, then, if well tolerated, increase to 2.5 mg once daily for 1 week, then to 3.75 mg once a day for 1 week, then 5 mg a day, for 4 weeks, then 7.5 mg once a day for 4 weeks, then 10 mg once a day, up to 10 mg a day.
Interaction of Betapro 2.5 Tablet
Bisoprolol should not be combined with other beta blockers.
Contraindications
In patients with cardiogenic shock, obvious heart failure, second or third degree atrioventricular block, right ventricular failure secondary to pulmonary hypertension , and sinus bradycardia.
Side-Effects of Betapro 2.5 Tablet
There may be gastrointestinal disorders, bradycardia, hypotension, headache, fatigue, sleep disturbance, dizziness, dizziness, thrombocytopenia, visual disturbance, and hair loss.
Pregnancy & Lactation
The safety of bisoprolol during pregnancy has not been established. There are no data on breastfeeding.
Precautions & Warnings
During long-term treatment with bisoprolol, kidney, liver and hematopoietic functions should be monitored regularly.
Therapeutic Class
Anti adrenergic agent (Beta blockers),Beta-adrenoceptor blocking drugs,Beta-blockers
Storage Conditions
Store in a dry place away from light and heat. Keep out of reach of children